眼の発生
Cvekl et al., 2014 Development Fig.3
レンズがあれほど透明な理由
Terminal differentiation of lens fiber cells occurs by loss of organelles and degradation of DNA. https://www.sciencedirect.com/sdfe/pdf/download/eid/1-s2.0-S0301468111613923/first-page-pdf
レビュー論文
- Aleš Cvekl, Ruth Ashery-Padan. The cellular and molecular mechanisms of vertebrate lens development. Development 2014 141: 4432-4447; doi: 10.1242/dev.107953
- F. J. Lovicu,J. W. McAvoy, and R. U. de Iongh. Understanding the role of growth factors in embryonic development: insights from the lens. Philos Trans R Soc Lond B Biol Sci. 2011 Apr 27; 366(1568): 1204–1218. doi: 10.1098/rstb.2010.0339
- Lena Gunhaga. The lens: a classical model of embryonic induction providing new insights into cell determination in early development. Philos Trans R Soc Lond B Biol Sci. 2011 Apr 27; 366(1568): 1193–1203. doi: 10.1098/rstb.2010.0175
- F.J.Lovicu, J.W.McAvoy. Growth factor regulation of lens development. Developmental Biology
Volume 280, Issue 1, 1 April 2005, Pages 1-14 https://doi.org/10.1016/j.ydbio.2005.01.020 - Hajime Ogino and Kunio Yasuda. Sequential activation of transcription factors in lens induction. First published: 25 December 2001 Development, Growth & Differentiation https://doi.org/10.1046/j.1440-169x.2000.00532.x
原著論文
- Toshiaki Mochizuki, Yutaka Kojima, Yuko Nishiwaki, Tetsuya Harakuni, Ichiro Masai. Endocytic trafficking factor VPS45 is essential for spatial regulation of lens fiber differentiation in zebrafish. Development 2018 145: dev170282 doi: 10.1242/dev.170282 Published 15 October 2018
- Thuzar Thein, Jimmy de Melo, Cristina Zibetti, Brian S. Clark, Felicia Juarez, Seth Blackshaw. Control of lens development by Lhx2-regulated neuroretinal FGFs. Development 2016 143: 3994-4002; doi: 10.1242/dev.137760
- Dylan S. Audette, Deepti Anand, Tammy So, Troy B. Rubenstein, Salil A. Lachke, Frank J. Lovicu, Melinda K. Duncan. Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression Development 2016 143: 318-328; doi: 10.1242/dev.127860
- Faber et al., Fgf receptor signaling plays a role in lens induction. Development 128, 4425-4438 (2001) 4425 PDF
- Yasuhide Furuta and Brigid L.M. Hogan. BMP4 is essential for lens induction in the mouse embryo. Genes & Dev. 1998. 12: 3764-3775 doi:10.1101/gad.12.23.3764
- Steven Bassnett, Danijela Mataic. Chromatin Degradation in Differentiating Fiber Cells of the Eye Lens. Journal of Cell Biology 7 April 1997; 137 (1): 37 DOI: 10.1083/jcb.137.1.37 | Published April 7, 1997